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James E.K. Hildreth, PhD, M.D.

Director and Professor, Department of Internal Medicine

Nashville, TN

Meharry Medical College School of Medicine
Center for Health Disparities Research in HIV

 

 

         
 

James E.K. Hildreth, PhD, M.D.

 
 

HIV/AIDS

 
         
 
         
         
    Dr. James E. K. Hildreth is known internationally for his scientific accomplishments on the role of cholesterol in the Biology of Human Retroviruses, HIV and HTLV-1. This research discovered that cholesterol plays a profound role in HIV’s ability to penetrate cells. Hildreth documented that by removing the fatty material from the virus’s membrane the infection could be blocked from spreading. Consequently, his research documented that without fatty material; AIDS could not enter cells, and ultimately could not infect and spread throughout the human body. Currently, he is pioneering the development of a “chemical condom” to block the sexually transmission of HIV, herpes simplex virus, and other sexual-transmitted diseases (STD) pathogens.

Hildreth is recognized as being the first African American Rhodes Scholar from his hometown Camden, Arkansas. He graduated Magna Cum Laude in Chemistry from Harvard University. Next, Taylor enrolled at Oxford University in England, graduating with a Ph.D in Immunology. Upon returned to the United States, he obtained his M.D. and completed his postdoctoral fellowship in pharmacology at John Hopkins Medical School. He joined the Hopkins faculty as Assistant Professor and later made history. Dr. Hildreth became the first African American in the 125-year history at John Hopkins School of Medicine to earn full Professorship with tenure in the basic sciences. He later served for several years as the first Associate Dean for Graduate Studies.

Dr. Hildreth currently serves as the Director of the Center for AIDS Health Disparities Research, a National Institutes of Health (NIH) funded center and Professor of Internal Medicine at Meharry Medical College.
He has published more than 80 scientific articles and holds 6 patents. One protein discovered by Dr. Hildreth at Oxford is the basis for the Genentech drug RAPTIVA, approved by the FDA for treatment of psoriasis.

Dr. Hildreth has received numerous awards and honors: The Merck Index Award to Outstanding Students in Chemistry Award; Louis and Gustavus Pfeiffer Scholar in Pharmacology and Experimental Therapeutics; The William and Charlotte Cadbury Award; The Kaiser Foundation Award; Finalist, Markey Scholars Program, Markey Trust; Presidential Young Investigator Award, National Science Foundation; NIH Director’s Wednesday Lecture Series; Minority Access Alumnus Role Model Award; The Ranice W. Crosby Distinguished Service Award, John Hopkins University School of Medicine; and the Visionary Research Award, National Medical Fellowship.
   
         
         
         
 
         
 

 

 
         
         
    NIH Award Number: RR020405-02